International Journal of Life Science and Engineering
Articles Information
International Journal of Life Science and Engineering, Vol.1, No.4, Sep. 2015, Pub. Date: Jul. 15, 2015
Plasma Activity of Tartrate Resistant Acid Phosphatase in Acute Malaria Infection
Pages: 183-188 Views: 2869 Downloads: 997
[01] Abubakar El-Ishaq, School of Science and Technology, Science Laboratory Technology Department, Biochemistry, Hemistry Unit, Federal Polytechnic Damaturu, Yobe State, Nigeria.
[02] Timothy O. Omoluabi, School of Science and Technology, Science Laboratory Technology Department, Biochemistry, Hemistry Unit, Federal Polytechnic Damaturu, Yobe State, Nigeria.
Enzymes are biological molecules that modulate rate of chemical reactions within an optimum temprature and Hydrogen potential without themselve been used up.The activity of tartrate-resistant acid phosphatase E.C . Orthophosphoric monoester phosphohydrolase was assayed using the plasma of patient presenting with acute malaria. Objective of this study is to explore an alternative enzymatic approaches for diagnosis of severe malarial parasite infection. Total plasma tartrate-resistant acid phosphatase was assayed according to procedure of (Henry and Steer, 1999).The results obtained showed mean activity of 69.09±1.56IU, 110.02±0.74IU and 125.46±0.79IU, for infected male adults, female adults, and children respectively. These were found to differ significantly (p >0.05) from that of normal adult Males, Females and Children having mean activities of 182.68±0.93IU, 162.01±0.79IU and 178.37±1.03IU respectively. The research work revealed plasma activities of tartrate-resistant acid phosphatase for infected males, females and children, this means that tartrate resistance acid Phosphatase may possibly serves as an index in diagnosis of malaria parasite infection and its severity.
Tartarate, Phosphatase, Malaria, Damaturu, Plasmodium, Marker Enzyme
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