American Journal of Microbiology and Immunology
Articles Information
American Journal of Microbiology and Immunology, Vol.1, No.1, Jul. 2016, Pub. Date: Jun. 17, 2016
Inhibitory Effect of Selected Ghanaian Clay Leachates on Some Pathogenic Microbes
Pages: 1-5 Views: 2295 Downloads: 1088
Authors
[01] Lawrence Sheringham Borquaye, Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana; Central Laboratory, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
[02] Edward Ocansey, Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
[03] Julius Semenya, Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Abstract
Clay and other mineral products have been documented as remedies for numerous human diseases throughout history with a number of success stories. In this study, the antimicrobial activity of the aqueous leachates of five clay samples collected from Keta, Anloga, Half-Assini, Sogakope and Savietula, all in Ghana, were examined. The in vitro antimicrobial activity of the aqueous leachates were tested against nine microbes using agar well diffusion assay. Of the five clay samples, Sogakope clay leachate possessed the highest antimicrobial activity, showing varying zones of inhibitions against all nine test microorganisms. All other leachates exhibited antimicrobial activity against at least one of the test microbes, except for clay leachate from Anloga which was inactive towards all microbes used in this study. pH and conductivity measurements indicated that Sogakope aqueous leachate had the lowest pH of 2.81 and a conductivity of 54.2 μS/cm while aqueous leachates of Anloga, Keta, Half-Assini and Savietula clays had pH values of 10.27, 7.66, 4.88, 8.01 and conductivities of 94.8, 5.86, 2.02, 91.40 μS/cm respectively. Metal analysis revealed that all clay samples have comparable compositions. Clay deposits may potentially provide cost-effective topical antibacterial treatments.
Keywords
Agar Diffusion, Leachates, Metal Ions, Conductivity, pH
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